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Relative Bioavailability of Zinc Oxide

2021-03-31

The relative bioavailability of zinc oxide varies greatly; there is a low relative bioavailability of zinc oxide produced by fire method (39%) and a high relative bioavailability of zinc oxide produced by wet method (93%);


Comparison of the effects of zinc oxide with different bioavailability produced by the two methods on the growth of piglets:

*A study reported that 60 28-day-old weaned piglets were divided into 5 groups and were given 0, 1500 mg/kg fire-method or wet-method zinc oxide non-resistant diets for 21 days. Adding zinc oxide can promote growth performance. The growth of wet zinc oxide was faster than that of fire zinc oxide at 1 week, but the trend slowed down at 2 weeks. Neither zinc source has any effect on the crypt depth, villi height and width of the duodenum, jejunum and ileum.

*The same study reported that 48 21-day-old weaned piglets were divided into 4 groups. They were given 0, 1500 mg/kg fire-method or wet-method zinc oxide non-resistant diet for 17 days. The addition of zinc oxide can promote growth performance, but two types of zinc There is no difference between sources.

*The same study also reported that 60 weaned piglets at 28 days of age were divided into 5 groups and were given 0, 1500 mg/kg fire or wet zinc oxide diets for 11 days. Adding zinc oxide to the first 6 days can promote growth performance and wet oxidation. The weight gain of zinc tends to be faster than that of fire method, but there is no difference in weight gain between the two zinc sources in the whole 11 days.

Whether or not antibiotics are added, the relative bioavailability of zinc oxide will not affect its growth-promoting effect on piglets.